Biomaterial Implants in Bone Fractures Produced in Rats Fibulas

نویسندگان

  • Henrique Yassuhiro Shirane
  • Diogo Yochizumi Oda
  • Thiago Cerizza Pinheiro
  • Marcelo Rodrigues da Cunha
چکیده

UNLABELLED To evaluate the importance of collagen and hydroxyapatite in the regeneration of fractures experimentally induced in the fibulas of rats. METHOD 15 rats were used. These were subjected to surgery to remove a fragment from the fibula. This site then received a graft consisting of a silicone tubes filled with hydroxyapatite and collagen. RESULTS Little bone neoformation occurred inside the tubes filled with the biomaterials. There was more neoformation in the tubes with collagen. CONCLUSION The biomaterials used demonstrated biocompatibility and osteoconductive capacity that was capable of stimulating osteogenesis, even in bones with secondary mechanical and morphological functions such as the fibula of rats.

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عنوان ژورنال:

دوره 45  شماره 

صفحات  -

تاریخ انتشار 2010